#VascularAging - #AgeArtériel - #ArterialStiffness -RigiditéArtérielle

Vascular ageing biomarkers have been found to be predictive of CV risk independently of classical risk factors, and yet are not widely used in clinical practice. 

Age is a key risk factor for hypertension and cardiovascular disease (CVD).1 A major consequence of ageing is the progressive stiffening of the major arteries, particularly the proximal aorta.

Arterial stiffness is a promising marker of vascular ageing and many studies have shown that the stiffness of the large arteries is related to elevated CVD risk in adults, independently of traditional cardiovascular risk factors.4 Given the world’s ageing population, effective monitoring of vascular ageing is increasingly important, and clinical biomarkers that can accurately describe the status of the vasculature are highly desirable.5

This review focuses on arterial stiffness biomarkers such as pulse wave velocity (PWV), given the wealth of evidence that they can capture age-related arteriosclerotic changes.

The arterial pulse wave is a rich source of information for assessing vascular health in humans as it is influenced by the cardiac and vascular properties80 and thus can reflect physiological changes in the cardiovasculature.80–82 Arterial pulse signals are measured in both clinical practice and wearable devices. Two commonly obtained pulse signals are the PPG and radial BP. Numerous physiological parameters can be computed from these signals, which can be useful for health monitoring and clinical decision-making. 

Axelife® SAS is a French company that, since its formation in 2010, has specialized in the field of health. It designs and develops medical devices, and its flagship product, the “pOpmètre®”, is a device that diagnoses arteriosclerosis and accelerated arterial aging.

https://www.axelife.fr/en/axelife-en/