CARDIOVASCULAR RISKS & DISEASES - RISQUES & MALADIES CARDIOVASCULAIRES

This cross-sectional study evaluates associations between environmental burden and cardiovascular risk factors and diseases at the neighborhood level and by levels of social vulnerability.

This economic evaluation estimates the cost-effectiveness of implementing a pharmacist-prescribing intervention to improve blood pressure control in the US.

D'après les données d'Eurostat publiées le 7 mars, le Covid-19 a été la troisième cause de décès dans l'UE en 2020, derrière les maladies cardiovasculaires et le cancer.

COVID-19-associated vascular disease complications are primarily associated with endothelial dysfunction; however, the consequences of disease on vascular structure and function, particularly in the long term (>7 weeks post-infection), remain unexplored. Individual pre- and post-infection changes in arterial stiffness as well as central and systemic hemodynamic parameters were measured in patients diagnosed with mild COVID-19. As part of in-laboratory observational studies, baseline measurements were taken up to two years before, whereas the post-infection measurements were made 2–3 months after the onset of COVID-19. We used the same measurement protocol throughout the study as well as linear and mixed-effects regression models to analyze the data. Patients (N = 32) were predominantly healthy and young (mean age ± SD: 36.6 ± 12.6). We found that various parameters of arterial stiffness and central hemodynamics—cfPWV, AIx@HR75, and cDBP as well as DBP and MAP—responded to a mild COVID-19 disease. The magnitude of these responses was dependent on the time since the onset of COVID-19 as well as age (pregression_models ≤ 0.013). In fact, mixed-effects models predicted a clinically significant progression of vascular impairment within the period of 2–3 months following infection (change in cfPWV by +1.4 m/s, +15% in AIx@HR75, approximately +8 mmHg in DBP, cDBP, and MAP). The results point toward the existence of a widespread and long-lasting pathological process in the vasculature following mild COVID-19 disease, with heterogeneous individual responses, some of which may be triggered by an autoimmune response to COVID-19.

The paper concludes the results have important implications for understanding the long-term cardiovascular consequences of COVID-19 infection and may guide prevention and management strategies for associated vascular disease.

Aim: To assess changes in blood pressure (BP) and arterial stiffness among 84 rotating shift and 25 dayworkers (control subjects) at two industrial plants during a 4-year follow-up, and to assess changes in outcome variables among shift workers at the two plants after a reduction in the number of night shifts during the last year of follow-up in one of the plants. Methods: We collected demographic data using a questionnaire, examined systolic and diastolic blood pressure (sBP, dBP), central systolic and diastolic aorta pressure (cSP, cDP), augmentation pressure (AP), central pulse pressure (cPP), and pulse wave velocity (PWV). We registered sleep quality. The last 4–14 months of follow-up one plant implemented a 12-week shift plan reducing the total number of night shifts and consecutive night shifts from 16.8 to 14 and from 7.2 to 4. To assess differences in change of outcomes between study groups we applied linear mixed models. Results: The dayworkers were older, more hypertensive, reported less sleep disturbance, and smoked/snuffed less than the shift workers did. The adjusted annual increase in PWV was 0.34 m/s (95%CI, 0.22, 0.46) among shift workers and 0.09 m/s (95%CI, −0.05, 0.23) in dayworkers, yielding a significant difference of change of 0.25 m/s (95%CI, 0.06, 0.43). No significant differences were found between the two groups of shift workers in any cardiovascular disease (CVD) outcome during the last year of follow-up. Conclusions: Shift work in industry is associated with arterial stiffness, reflecting an increased risk of future CVD. No significant changes in arterial stiffness were identified as a consequence of a small reduction in the number of night shifts and consecutive night shifts.

Une nouvelle recherche – financée par la Medical Research Foundation – a montré une forte augmentation de l’incidence des accidents vasculaires cérébraux chez les jeunes adultes, dans une étude portant sur plus de 94 000 personnes dans l’Oxfordshire. L’AVC est un problème de santé majeur qui peut avoir des conséquences dévastatrices. Cela se produit lorsque […]

Dans une large étude rétrospective de cohorte, des chercheurs français ont exploré l’évolution de l’incidence de l’insuffisance cardiaque, en particulier chez les adultes de moins de 50 ans. Les résultats interpellent…

Pour conclure, deux points forts sont à retenir :
les populations à haut risque et très haut risque sont clairement définies et doivent faire l'objet de toutes les attentions en termes de prévention ;
le premier traitement, commun à toutes les situations, préalable et contemporain d'éventuels traitements médicamenteux, est la modification des habitudes de vie.

Les femmes plus exposées aux facteurs de risque
Le mode de vie des femmes a fortement évolué ces 30 dernières années,
entrainant une progression régulière de leur exposition aux facteurs de risque cardio-vasculaire.

Après avoir régulièrement diminué ces dernières décennies, la consommation d’alcool stagne en France. Environ un quart des adultes ont toujours une consommation qui dépasse les repères préconisés. Ces personnes s’exposent dès lors à des complications hépatiques, cardiovasculaires, neurologiques ainsi qu’à un risque majoré de cancers. L’alcool reste ainsi la deuxième…

Cardiovascular disease (CVD) mortality increased during the initial years of the coronavirus
disease 2019 (COVID-19) pandemic, but whether these trends endured in 2022 is unknown.
The analysis describes temporal trends in CVD death rates from 2010 to 2022 and estimates
excess CVD deaths from 2020 to 2022.

Les maladies cardiovasculaires ou cardio-neurovasculaires sont la première cause de mortalité dans le monde, la deuxième en France après les cancers. Malgré quatre décennies de baisse de mortalité et…

Higher aortic stiffness was associated with loss of physical function over approximately 11 years, said Sahni, an associate scientist at the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife. Arterial stiffening results from decreased blood flow with aging, leading to declines in muscle mass. Few studies have specifically looked at the role of vascular function and changes in functional mobility and muscle strength.


Future studies, the researchers said, should look at whether interventions that target vascular health reduce age-related declines in physical function. Sahni said that the research is important because many individuals could be helped.

“There is a need for development of novel interventions that target prevention of physical limitations in older adults,” she said.

Influence of Shift Work on Arterial Stiffness and Systemic Inflammation. A 3-Year Follow-Up Study in Industry

In a groundbreaking study, researchers have shed light on a compelling connection between insulin resistance and an elevated risk of stroke. This | DH Latest News, DH NEWS, Latest News, Diseases & Remedies, NEWS, Wildlife, Health , public health, chronic inflammation, preventive measures, collaborative efforts, cardiovascular health, blood clotting, patient outcomes, early detection, healthcare systems, healthcare, insulin resistance, societal health, intervention, metabolic health, research study, insulin sensitivity, lifestyle modifications, clinical management, stroke risk, vascular health

s, and maximal oxygen uptake. We assessed blood samples for determination of lipids, glycosylated hemoglobin, C-reactive protein, markers of inflammation, and particle concentrations/respirable dust. Baseline comparisons were analyzed using logistic regression (plaque) and linear regression for all other outcomes. We applied mixed models to assess differences in change in health outcomes between the shift workers and the day workers.

Results

At baseline, the adhesion molecules soluble vascular cell adhesion molecule 1 and soluble P-selectin were elevated among the shift workers compared with that of the day workers. There was a significant difference in change in pulse wave velocity between shift workers (1.29-m/s increase) and day workers (0.11-m/s increase) over the 3-year follow-up. Respirable dust levels were below the Norwegian occupational exposure limit.

Conclusions

Shift work in industry is associated with arterial stiffening reflecting increased risk for future cardiovascular disease. More uncertainly, we found some support for systemi

In a meta-analysis, Vlachopoulos et al. demonstrated that arterial stiffness, expressed as PWV, is a strong predictor of future cardiovascular events and all causes of mortality [13]. In the same meta-analysis, these researchers verified that for every 1m/s increase in PWV, the risk of developing a cardiovascular event increases by 14%. They also demonstrated that the ability to predict arterial stiffness is greater in individuals with a higher baseline cardiovascular risk [13].

Japan ranks the highest globally, in terms of longevity. The average life expectancy was 81.4 years for men and 87.5 years for women in 2019. Such success in health is attributable to the substantial reduction in age-standardized mortality from cardiovascula

La Société Française de Cardiologie et la fondation Cœur & Recherche lacent une levée de fonds, suivi d'un appel à projet afin de comprendre et d’enr1

Risque cardiovasculaire : évaluation et prévention - recommandations VIDAL : La maladie, Diagnostic, Quels patients traiter ?, Objectifs de la prise en charge, Prise en charge